Cervical cancer is the most common gynecologic malignancy and the fourth most common cancer in women worldwide. Over the last two decades, minimally invasive surgery (MIS) has emerged as the mainstay in the surgical management of early-stage cervical cancer, bringing advan-tages such as a lower operative morbidity and shorter hospital stay compared to open surgery, while maintaining comparable oncologic outcomes in numerous retrospective studies. Considering onco-logical patients, it is mandatory to assess the oncological outcomes and safety of this type of surgery. Moreover, there are different future outlooks on cervical cancer therapy, based on immunotherapy, target therapy, and poly-ADP-ribose polymerases (PARP) inhibitors in combination with each other, and in combination with standard chemotherapy and radiotherapy. The goal is to find an approach that is as personalized as possible.

New Advances in Cervical Cancer: From Bench to Bedside / D'Oria, Ottavia; Corrado, Giacomo; Simone Laganà, Antonio; Chiantera, Vito; Vizza, Enrico; Giannini, Andrea. - In: INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH. - ISSN 1660-4601. - 19:12(2022). [10.3390/ijerph19127094]

New Advances in Cervical Cancer: From Bench to Bedside

Ottavia D’Oria;Andrea Giannini
2022

Abstract

Cervical cancer is the most common gynecologic malignancy and the fourth most common cancer in women worldwide. Over the last two decades, minimally invasive surgery (MIS) has emerged as the mainstay in the surgical management of early-stage cervical cancer, bringing advan-tages such as a lower operative morbidity and shorter hospital stay compared to open surgery, while maintaining comparable oncologic outcomes in numerous retrospective studies. Considering onco-logical patients, it is mandatory to assess the oncological outcomes and safety of this type of surgery. Moreover, there are different future outlooks on cervical cancer therapy, based on immunotherapy, target therapy, and poly-ADP-ribose polymerases (PARP) inhibitors in combination with each other, and in combination with standard chemotherapy and radiotherapy. The goal is to find an approach that is as personalized as possible.
2022
cancer therapy; cervical cancer; gynecological cancer surgery; targeted therapy; Female; Humans; Minimally Invasive Surgical Procedures; Poly(ADP-ribose) Polymerases; Retrospective Studies; Genital Neoplasms, Female; Uterine Cervical Neoplasms
01 Pubblicazione su rivista::01m Editorial/Introduzione in rivista
New Advances in Cervical Cancer: From Bench to Bedside / D'Oria, Ottavia; Corrado, Giacomo; Simone Laganà, Antonio; Chiantera, Vito; Vizza, Enrico; Giannini, Andrea. - In: INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH. - ISSN 1660-4601. - 19:12(2022). [10.3390/ijerph19127094]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/1652041
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